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Product Name | Rat NAP-2 protein |
Description | Neutrophil Activating Peptide 2 (NAP-2) is proteolytically processed carboxyl-terminal fragments of platelet basic protein (PBP)which is found in the alpha-granules of human platelets. NAP-2 is a member of the CXC chemokines. Similar to other ELRdomain containing CXC chemokines such as IL-8 and the GRO proteins, NAP-2 has been shown to bind CXCR-2 and tochemoattract and activate neutrophils. Although CTAP-III, C-TG and PBP represent amino-terminal extended variants of NAP-2and possess the same CXC chemokine domains, these proteins do not exhibit NAP-2 activity. Recently, it has been shown thatthe additional amino-terminal residues of CTAP-III masks the critical ELR receptor binding domain that is exposed on NAP-2and may account for lack of NAP-2 activity. MW: 6.8 kDa. Purity > 97% by SDS-PAGE and HPLC analyses |
Size | 2 ug, 10 ug, 1 mg, 100 ug, 250 ug, 500 ug |
Concentration | Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4. |
Applications | HPLC, SDS-PAGE |
Other Names | Rat NAP-2/CXCL7 protein |
Gene, Accession, CAS # | n/a |
Catalog # | orb107787 |
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Order / More Info | Rat NAP-2 protein from BIORBYT LTD. |
Product Specific References | n/a |
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