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| Product Name | Recombinant Human Histone PARylation factor 1 (HPF1) |
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| Description | Purity > 85% as determined by SDS-PAGE. MW: 59.4kDa. Full Length: 1-346aa. N-terminal 10xHis-SUMO-tagged and C-terminal Myc-tagged. Homo sapiens (Human). Acts as a cofactor for serine ADP-ribosylation by conferring serine specificity on PARP1 and PARP2: interacts with PARP1 and PARP1 and is able to change amino acid specificity toward serine. Promotes histone serine ADP-ribosylation in response to DNA damage, limiting DNA damage-induced PARP1 hyper-automodification, and ensuring genome stability |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | C4orf27 |
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| Gene, Accession, CAS # | HPF1, UniProt: Q9NWY4 |
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| Catalog # | RPC23569 |
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| Order / More Info | Recombinant Human Histone PARylation factor 1 (HPF1) from BIOMATIK |
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| Product Specific References | n/a |
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