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| Product Name | Ro 31-8425 HCl |
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| Description | Purity >98% by NMR, TLC. Ro 31-8425 is a selective, reversible, ATP-competitive inhibitor of protein kinase C. Inhibits PKCa, b1, b2, g and e, IC50= 8, 8, 14,13 and 39 nM respectively. Extremely useful tool for probing PKC-dependent physiology or signaling pathways. Increases MSC adhesion to an ICAM-1 coated substrate in vitro and enables targeted delivery of systematically administered MSCs to inflamed sites in vivo in a CD11a-dependent manner. Cell permeable. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-[8-(Aminomethyl)-6,7,8,9-tetrahydropyrido[1,2-a]indol-10-yl]-4-(1-methylindol-3-yl)pyrrol-2,5-dione hydrochloride |
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| Gene, Accession, CAS # | CAS: 145317-11-9 |
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| Catalog # | LS-H14830 |
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| Order / More Info | Ro 31-8425 HCl from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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