| 产品详情 |
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| Product Name | MPEP hydrochloride |
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| Description | Purity >98% by HPLC. MPEP hydrochloride is a highly selective and potent non-competitive antagonist at the mGlu5 (metabotropic glutamate receptor subtype 5) receptor subtype (IC50 = 36 nM). It is a positive allosteric modulator at mGlu4. MPEP hydrochloride reduces DHPG (S-3, 5-dihydroxyphenylglycine)-induced excitations but not the excitations induced by AMPA (-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid). In vivo studies show it reverses mechanical hyperalgesia in the inflamed rat hind paw. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-Methyl-6-(phenylethynyl)pyridine hydrochloride |
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| Gene, Accession, CAS # | CAS: 219911-35-0 |
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| Catalog # | LS-H3857 |
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| Price | |
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| Order / More Info | MPEP hydrochloride from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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