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Antigenic Specificity | ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | serum |
Size | 100 µL |
Concentration | n/a |
Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Function: This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. Defects in ATP2A1 are the cause of Brody myopathy (BRM). An autosomal recessive myopathy characterized by increasing impairment of relaxation of fast twist skeletal muscle during exercise.Subcellular location: Endoplasmic reticulum membrane, Multi-pass membrane protein. Sarcoplasmic reticulum membrane, Multi-pass membrane protein.Tissue specificity: Skeletal muscle, fast twitch muscle (type II) fibers. Also known as: AT2A1, Sarcoplasmic/endoplasmic reticulum calcium ATPase 1, Calcium pump 1, Calcium-transporting ATPase sarcoplasmic reticulum type, fast twitch skeletal muscle isoform, Endoplasmic reticulum class 1/2 Ca(2+) ATPase. |
Immunogen | A synthetic peptide from the n-terminal region of human SERCA1 (Calcium pump 1) conjugated to an immunogenic carrier protein was used as the antigen. |
Other Names | cb279|serca|serca1|wu:cegs655|wu:fb17h11|wu:fb19b10|zgc:92110|ATP2A1|atp2a|atp2a2|atp2b|ca-p60a|dar|serca2|SERCA1|ATP2A3|SERCA1a|Serca1|ATP2A |
Gene, Accession # | Gene ID: 487 |
Catalog # | ABIN572143 |
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Order / More Info | ATPase, Ca++ Transporting, Cardiac Muscle, Fast Twitch 1 (ATP2A1) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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