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Product Name | Growth Differentiation Factor 15 (GDF15) (Active) protein |
Description | GDF-15 belongs to the TGF beta cytokine family whose members play an important role during prenatal development and postnatal growth, remodeling and maintenance of a variety of tissues and organs. GDF-15 is expressed predominantly in placenta and to a much lesser extent in various other tissues. The presence of GDF-15 in amniotic fluid and its elevated levels in the sera of pregnant women suggest a role for GDF-15 in gestation and embryonic development. GDF-15 generally exerts tumor suppressive activities and is one of the predominant factors produced and secreted in response to activation of the p53 pathway. Interestingly, the serum level of GDF-15 is positively correlated with neoplastic progression of several tumor types, including certain colorectal, pancreatic, and prostate cancers. Alternative Names: GDF 15, GDF 15 protein, GDF15, GDF-15 protein, GDF-15, GDF-15 protein, Prostate differentiation factor protein, MIC-1 protein, Placental TGFbeta protein |
Size | 20 µg |
Concentration | n/a |
Applications | n/a |
Other Names | GDF15|GDF-15|MIC-1|MIC1|NAG-1|PDF|PLAB|PTGFB|SBF |
Gene, Accession, CAS # | Gene ID: 9518 |
Catalog # | ABIN935652 |
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Order / More Info | Growth Differentiation Factor 15 (GDF15) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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