| 产品详情 |
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| Antigenic Specificity | ADAM10 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ADAM10 Polyclonal Antibody. • Target Background: Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP). Contributes to the normal cleavage of the cellular prion protein. Inv |
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| Immunogen | KLH conjugated synthetic peptide derived from human ADAM10. Immunogen Range: 623-672/748 |
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| Other Names | RAK; kuz; AD10; AD18; MADM; CD156c; HsT18717; Disintegrin and metalloproteinase domain-containing protein 10; ADAM 10; CDw156; Kuzbanian protein homolog; Mammalian disintegrin-metalloprotease; ADAM10 |
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| Gene, Accession # | Gene ID: 102, SwissProt: O14672 |
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| Catalog # | bs-3574R |
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| Price | |
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| Order / More Info | ADAM10 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Li, Qing, et al. (2015) Gene. PubMed: 25703701 // Angenendt, L., et al. (2017) Leukemia. PubMed: 28663580 // Ku, Tingting, et al (2017) Part Fibre Toxicol. PubMed: 28851397 |
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