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| Product Name | Concanamycin B |
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| Description | Purity >95%. Concanamycin B is a macrolide antibiotic that selectively inhibits vacuolar type H+ -ATPases, also known as V-ATPases (IC50 = 5 nM). In this way, it blocks the acidification of vacuolar organelles as well as early to late endosomal transport. Concanamycin B interferes with bone resorption and maturation of CD8 T lymphocytes. It also prevents processing of major histocompatibility complex (MHC) class II precursors in human B cells, inhibiting the expression of MHC class II molecules on the cell surface. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (3Z,5E,7R,8R,9S,10S,11R,13E,15E,17S,18R)-18-[(1S,2R,3S)-3-[(2R,4R,5S,6R)-4-[[4-O-(aminocarbonyl)-2,6-dideoxy-β-D-arabino-hexopyranosyl]oxy]tetrahydro-2-hydroxy-5-methyl-6-(1E)-1-propenyl-2H-pyran-2-yl]-2-hydroxy-1-methylbutyl]-8,10-dihydroxy-3,17-dimethox, 8-deethyl-8-methyl-Concanamycin A, MCH 210 |
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| Gene, Accession, CAS # | CAS: 81552-33-2 |
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| Catalog # | LS-H7229 |
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| Order / More Info | Concanamycin B from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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