| 产品详情 |
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| Antigenic Specificity | Calcium Sensing Receptor |
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| Clone | 5C10, ADD |
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| Host Species | Mouse |
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| Reactive Species | bovine, human, mouse, rat |
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| Isotype | IgG2a |
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| Format | purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | ELISA: Assay dependent, Immunofluorescence: Assay dependent, Immunohistochemistry (Frozen): 2 µg/mL, Western Blot: 2 µg/mL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Calcium Sensing Receptor Monoclonal Antibody (5C10, ADD). The calcium sensing receptor (CaSR) has been shown to play a major role in regulating parathyroid hormone secretion and subsequently influencing the calcium concentration of extracellular fluids. Based on sequence analysis of cDNA clones it appears that the CaSR is similar to the 7-transmembrane-domain G-protein-coupled receptor superfamily. Changes in extracellular calcium are thought to modulate a balance between proliferation and differentiation in a variety of cell types. In normal primary keratinocytes and breast epithelial cells, proliferation is inhibited and elevated extracellular calcium levels trigger differentiation. Malignant transformations of these cell types are accomp |
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| Immunogen | n/a |
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| Other Names | CaSR, Parathyroid Cell calcium-sensing receptor |
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| Gene, Accession # | Entrez: 12374, 24247, 281038, 846; Uniprot: P35384, P41180, P48442, Q9QY96 |
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| Catalog # | MA1-934 |
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| Price | |
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| Order / More Info | Calcium Sensing Receptor Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 10196220, 14704232, 16455645, 17189274, 17267550, 20091482, 20233724, 20519369, 20682641, 20861236, 21135065, 21252045, 21393447, 21625458, 21750971, 21969374, 22295103, 22514536, 22517767, 22730443, 22886306, 24089267, 25270269, 25299122, 25331955, 25500736, 26661650, 27581537, 27760455, 27915449, 28094278 |
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