产品详情 |
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Antigenic Specificity | ME2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µg |
Concentration | n/a |
Applications | Immunofluorescence: 20 µg/mL, Immunohistochemistry (Paraffin): 5 µg/mL, Western Blot: 1-2 µg/mL |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ME2 Polyclonal Antibody. ME2 is a homotetrameric, mitochondrial NAD-dependent malic enzyme that catalyzes the oxidative decarboxylation of malate to pyruvate. It is related to malic enzyme 1 (ME1), a cytoplasmic NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The expression of both malic enzymes is reciprocally regulated by p53; this regulation has been shown to modulate metabolism and senescence. Certain single-nucleotide polymorphism haplotypes of the ME2 gene have been shown to increase the risk for idiopathic generalized epilepsy. |
Immunogen | n/a |
Other Names | ODS1, NAD-dependent malic enzyme, mitochondrial, Malic enzyme 2, NAD-ME |
Gene, Accession # | Entrez: 4200; Uniprot: P23368 |
Catalog # | PA5-38007 |
Price | |
Order / More Info | ME2 Antibody from INVITROGEN ANTIBODIES |
Product Specific References | n/a |
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