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Product Name | CSE1 Chromosome Segregation 1-Like (Yeast) (CSE1L) peptide |
Description | Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. CSE1L binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the protein may play a role both in apoptosis and in cell proliferation. |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
Other Names | BcDNA:LD14270|CAS|CG13281|Dcas|Dmel\\CG13281|cas|dcas|l(2)k03902|CSE1L|XPO2|Exportin-2|DKFZp459E1929|2610100P18Rik|AA407533|Capts|Cas|Xpo2|xpo2|CSE1 |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN937957 |
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Order / More Info | CSE1 Chromosome Segregation 1-Like (Yeast) (CSE1L) peptide from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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