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| Antigenic Specificity | Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (aa 123-137), (Middle Region) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | EIF2S1(Eukaryotic Translation Initiation Factor 2, Subunit 1), also called EIF2-alpha, is a protein that in humans is encoded by the EIF2S1 gene. Hartz(2010) mapped the EIF2S1 gene to chromosome 14q23.3 based on an alignment of the EIF2S1 sequence with the genomic sequence(GRCh37). Ernst et al.(1987) stated that protein synthesis is inhibited due to phosphorylation of Eif2-alpha in hemin-deprived rabbit reticulocyte lysates. HeLa cells subjected to heat shock, serum deprivation, or interferon treatment followed by virus infection also show a correlation between EIF2-alpha phosphorylation and translational repression. Jacob et al.(1989) found that the alpha-Pal transcription factor bound to 2 palindromic sites within the EIF2-alpha promoter and was essential for transcription of the EIF2-alpha gene. |
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| Immunogen | A synthetic peptide corresponding to a sequence in the middle region of human EIF2S1(123-137aa KDEQLESLFQRTAWV). |
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| Other Names | 0910001O23Rik|2410026C18Rik|35kDa|Eif2a|eIF2alpha|eif2|eif2s1|fb19d01|wu:fb19d01|EIF-2|EIF-2A|EIF-2alpha|EIF2|EIF2A|eif2a|CG9946|Dmel\\CG9946|Eif2alpha|IF2A_DROME|M(1)14C|M(1)19-153|M(1)8e3-10|deIF2alpha|eIF-2|eIF-2 a|eIF-2 alpha|eIF2 alpha|eIF2-alpha|eIF2a|eiF-2alpha|elF2alpha|l(1)14Cf|l(1)19-153 |
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| Gene, Accession # | Gene ID: 1965 |
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| Catalog # | ABIN1673514 |
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| Price | |
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| Order / More Info | Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1) (aa 123-137), (Middle Region) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 2948954, 2584221 |
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