| 产品详情 |
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| Antigenic Specificity | SMC1 phospho S957 |
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| Clone | 5D11.G5 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 kappa |
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| Format | Protein G purified |
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| Size | 100 µg |
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| Concentration | 1.0 mg/mL |
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| Applications | ELISA, IF Microscopy, Western Blot. Protein G Purified Mab anti-SMC1 was tested by ELISA, immunohistochemistry and western blotting against native protein. The antibody reacts with SMC1 from irradiated human and mouse cells. A 160 kDa band corresponding to human SMC1 is noted in |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This Protein G Purified Mab antibody is directed against human SMC1 and is useful in determining its presence in various assays. This monoclonal anti-SMC1 antibody recognizes the phosphorylated epitope in native and over-expressed proteins found in various tissues and extracts. Minimal reactivity is observed against the non-phosphorylated epitope. Reactivity is observed against human and mouse SMC1. Cross reactivity with SMC1 from other eukaryotic sources has not been tested. |
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| Immunogen | This antibody was produced from a synthetic peptide corresponding to aa 951-962 of human SMC1 by injection into a balb/c mouse. |
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| Other Names | mouse anti-SMC1 pS957 antibody, Structural maintenance of chromosomes protein 1B antibody, SMC1beta protein antibody, SMC1B antibody, SMC1L2 antibody |
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| Gene, Accession # | SMC1B, Gene ID: 27127, NCBI: Q8NDV3.2, UniProt: Q8NDV3 |
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| Catalog # | 200-301-397 |
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| Price | |
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| Order / More Info | SMC1 phospho S957 Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Kitagawa, R., Bakkenist, C.J., McKinnon, P.J. and Kastan, M.B. (2004) Phosphorylation of SMC1 is a critical downstream event in the ATM-NBS1-BRCA1 pathway. Genes Dev. 18(12):1423-1438.Callen E, Jankovic M, Wong N, Zha S, Chen HT, Difilippantonio S, Di Virgilio M, Heidkamp G, Alt FW, Nussenzweig A, Nussenzweig M. (2009) Essential Role for DNA-PKcs in DNA Double-Strand Break Repair and Apoptosis in ATM-Deficient Lymphocytes. Mol Cell. 34(3):285-97. |
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