| 产品详情 |
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| Product Name | Chidamide |
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| Description | Purity >98%. Chidamide is a histone deacetylase inhibitor that increases histone H3 acetylation levels in LoVo and HT-29 colon cancer cells at concentrations as low as 4 µM. Additionally, chidamide affects the activation of oncogenic signaling kinases by dose-dependently reducing phosphorylated Akt, mTOR, p70S6k, Raf, and Erk1/2 protein expression in colon cancer cells. Furthermore, chidamide treatment dose-dependently upregulates p21 protein expression, downregulates Cdk4, and induces cell cycle arrest at the G0 /G1 phase. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-(2-amino-5-fluorophenyl)-4-[[[1-oxo-3-(3-pyridinyl)-2-propen-1-yl]amino]methyl]-benzamide |
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| Gene, Accession, CAS # | CAS: 743420-02-2 |
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| Catalog # | LS-H7103 |
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| Price | |
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| Order / More Info | Chidamide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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| 产品资料 |
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