| 产品详情 |
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| Product Name | E-64c |
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| Description | Purity >98%. Cysteine proteases are a class of enzymes containing an active-site cysteine residue that are important in protein degradation pathways. E-64c is a synthetic analog of E-64, a potent and irreversible cysteine protease inhibitor isolated from Aspergillus japonicus. E-64c inhibits the cysteine proteases cathepsin B and cathepsin L from rat liver with IC50 values of 8.7 and 3.5 nM, respectively. The ethyl ester of E-64c, E-64d, is cell permeable and hydrolyzed in cell culture to E-64c. E-64d arrests the growth of A431 cells in metaphase at concentrations between 20-200 µg/ml. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | (2S,3S)-3[[(1S)-3-methyl-1-[[(3-methylbutyl)amino]carbonyl]butyl]amino]carbonyl]-oxiranecarboxylic acid, EP 475, Loxistatin Acid, NSC 694279 |
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| Gene, Accession, CAS # | CAS: 76684-89-4 |
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| Catalog # | LS-H7610 |
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| Order / More Info | E-64c from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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