产品详情 |
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Antigenic Specificity | PFK2 Ser467 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Alexa Fluor® 488 conjugate |
Size | 100ul |
Concentration | 1ug/ul |
Applications | IF(IHC-P) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | PFK2 (Ser467) Polyclonal Antibody, Alexa Fluor® 488 Conjugated. • Target Background: 6 Phosphofructo 2 Kinase plays a role in the synthesis and degradation of fructose 2,6-bisphosphate. Fructose-2,6-bisphosphate acts as an allosteric regulator of 6-phosphofructo-1-kinase (PFK1), which catalyses a key step in the glycoytic pathway. Glycolytic flux is key to tumour growth, and small molecule inhibition of 6 Phosphofructo 2 Kinase suppresses both glycolytic flux and tumour growth. Several lines of evidence suggest that 6 Phosphofructo 2 Kinase is also involved in obesity. |
Immunogen | KLH conjugated synthetic phosphopeptide derived from human PFK2 around the phosphorylation site of Ser467. Immunogen Range: 458-520/520 |
Other Names | Phosphorylated, phospho-PFK2; IPFK2; 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3; 6PF-2-K/Fru-2,6-P2ase 3; PFK/FBPase 3; 6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme; Renal carcinoma antigen NY-REN-56; iPFK-2; PFKFB3 |
Gene, Accession # | Gene ID: 5209, SwissProt: Q16875 |
Catalog # | bs-3331R-A488 |
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Order / More Info | PFK2 Ser467 Antibody from BIOSS ANTIBODIES |
Product Specific References | n/a |
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