| 产品详情 |
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| Product Name | Recombinant Mouse C-type lectin domain family 4 member E (Clec4e), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 23.6kDa. Extracellular Domain: 46-214aa. N-terminal 6xHis-tagged. Mus musculus (Mouse). C-type lectin that functions as cell-surface receptor for a wide variety of ligands such as damaged cells, fungi and mycobacteria. Plays a role in the recognition of pathogenic fungi, such as Candida albicans. The detection of mycobacteria is via trehalose 6,6'-dimycolate (TDM), a cell wall glycolipid. Specifically recognizes alpha-mannose residues on pathogenic fungi of the genus Malassezia. Recognizes also SAP130, a nuclear protein, that is released by dead or dying cells. Transduces signals through an ITAM-containing adapter protein, Fc receptor gamma chain /FCER1G. Induces secretion of inflammatory cytokines through a pathway that depends on SYK, CARD9 and NF-kappa-B. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | C-type lectin superfamily member 9; Macrophage-inducible C-type lectin |
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| Gene, Accession, CAS # | Clec4e, UniProt: Q9R0Q8 |
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| Catalog # | RPC23596 |
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| Price | |
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| Order / More Info | Recombinant Mouse C-type lectin domain family 4 member E (Clec4e), partial from BIOMATIK |
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| Product Specific References | n/a |
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