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Product Name | Recombinant Mouse Granulin / GRN / Progranulin Protein (His tag) |
Description | MW: 63,458 Da. Purity >90 % as determined by SDS-PAGE. Background: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage |
Size | 0.05 mg, 0.1 mg |
Concentration | n/a |
Applications | The secreted recombinant mouse GRN comprises 583 amino acids and has a predicted molecular mass of 63 kDa. As a result of glycosylation, the apparent molecular mass of rmGRN is approximately 70-90 kDa in SDS-PAGE under reducing conditions. |
Other Names | [RP23-226P4.4, epithelin] |
Gene, Accession, CAS # | GRN, Gene ID: 14824, Accession: NP_032201.2 |
Catalog # | MBS2547003 |
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Order / More Info | Recombinant Mouse Granulin / GRN / Progranulin Protein (His tag) from MYBIOSOURCE INC. |
Product Specific References | n/a |
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