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| Product Name | Recombinant Human DNA-binding protein inhibitor ID-2 |
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| Description | 1-134aa; Full Length. MW: 30.9kD. Purity >90% as determined by SDS-PAGE. Transcriptional regulator (lacking a basic DNA binding domain) which negatively regulates the basic helix-loop-helix (bHLH) transcription factors by forming heterodimers and inhibiting their DNA binding and transcriptional activity. Implicated in regulating a variety of cellular processes, including cellular growth, senescence, differentiation, apoptosis, angiogenesis, and neoplastic transformation. Inhibits skeletal muscle |
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| Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.05 mg (Yeast) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Class B basic helix-loop-helix protein 26; bHLHb26; Inhibitor of DNA binding 2; Inhibitor of differentiation 2] |
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| Gene, Accession, CAS # | ID2, Gene ID: 3398, Accession: NP_002157.2 |
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| Catalog # | MBS969543 |
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| Order / More Info | Recombinant Human DNA-binding protein inhibitor ID-2 from MYBIOSOURCE INC. |
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| Product Specific References | Id-related genes encoding helix-loop-helix proteins are required for G1 progression and are repressed in senescent human fibroblasts.Hara E., Yamaguchi T., Nojima H., Ide T., Campisi J., Okayama H., Oda K.J. Biol. Chem. 269:2139-2145(1994) A human Id-like helix-loop-helix protein expressed during early development.Biggs J., Murphy E.V., Israel M.A.Proc. Natl. Acad. Sci. U.S.A. 89:1512-1516(1992) Orphan nuclear receptor small heterodimer partner, a novel corepressor for a basic helix-loop-helix t |
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