产品详情 |
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Product Name | 3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) peptide |
Description | 3-Hydroxyanthranilate 3,4-dioxygenase is a monomeric cytosolic protein belonging to the family of intramolecular dioxygenases containing nonheme ferrous iron. It is widely distributed in peripheral organs, such as liver and kidney, and is also present in low amounts in the central nervous system. HAAO catalyzes the synthesis of quinolinic acid (QUIN) from 3-hydroxyanthranilic acid. QUIN is an excitotoxin whose toxicity is mediated by its ability to activate glutamate N-methyl-D-aspartate receptors. Increased cerebral levels of QUIN may participate in the pathogenesis of neurologic and inflammatory disorders. |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
Other Names | Afu2g17450|0610007K21Rik|0610012J07Rik|3-HAO|3-HAOxase|3HAO|zgc:103585|HAO |
Gene, Accession, CAS # | n/a |
Catalog # | ABIN939222 |
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Order / More Info | 3-hydroxyanthranilate 3,4-Dioxygenase (HAAO) peptide from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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