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| Product Name | SIGIRR,Fc, Recombinant, Human |
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| Description | Purity >90% (SDS-PAGE). SIGIRR acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Sequence: Signal peptide and extracellular domain of human SIGIRR (aa 1-118) are fused at the C-terminus to the Fc portion of human IgG1. |
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| Size | 10ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | SIGIRR,Fc, Recombinant, Human (Toll/Interleukin-1 Receptor 8, TIR8, Single Ig IL-1R-related Molecule) |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | 45281 |
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| Order / More Info | SIGIRR,Fc, Recombinant, Human from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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