| 产品详情 |
| Edit |   |
|---|
| Product Name | EphA1, Fc Chimera, Recombinant, Human |
|---|
| Description | Purity ~95% (SDS-PAGE). Ephrin-A1, also known as B61 and LERK-1, is a member of the Ephrin-A family of GPI-anchored ligands that bind and induce the tyrosine autophosphorylation of Eph receptors. Ephrin-A ligands are structurally related to the extracellular domains of the transmembrane Ephrin-B ligands. Eph-Ephrin interactions are widely involved in the regulation of cell migration, tissue morphogenesis, and cancer progression. Human Ephrin-A1 is synthesized with an 18aa signal peptide, a 164aa mature chain, and a 23aa C-terminal propeptide which is removed prior to GPI linkage of Ephrin-A1 to the membrane. It can also be released as a soluble molecule. The mature 21-25kD human Ephrin-A1 shares 85% aa sequence identity with mouse and rat Ephrin-A1. Alternate splicing generates an additional isoform that lacks 22aa in the juxtamembrane region. This short isoform is also expressed on the cell surface and exhibits weakened binding to EphA2. Ephrin-A1 is widely expressed on endothelial an |
|---|
| Size | 50ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | EphA1, Fc Chimera, Recombinant, Human (Ephrin-A1, EPH-related Receptor Tyrosine Kinase Ligand 1, LERK-1, Immediate Early Response Protein B61, Tumor Necrosis Factor alpha-induced Protein 4, TNF alpha-induced Protein 4, EFNA1, EPLG1, LERK1, TNFAIP4) |
|---|
| Gene, Accession, CAS # | SwissProt: P20827 |
|---|
| Catalog # | E3355-01D |
|---|
| Price | |
|---|
| Order / More Info | EphA1, Fc Chimera, Recombinant, Human from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|