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| Antigenic Specificity | TrxR1 |
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| Clone | 5A5 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | purified |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA: Assay dependent, Immunoprecipitation: 1-2 µL |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | TrxR1 Monoclonal Antibody (5A5). The mammalian thioredoxin reductases (TrxRs) are a family of selenocysteine-containing pyridine nucleotide-disulfide oxidoreductases. All the mammalian TrxRs are homologous to glutathione reductase with respect to primary structure including the conserved redox catalytic site (-Cys-Val-Asn-Val-Gly-Cys-) but distinctively with a C-terminal extension containing a catalytically active penultimate selenocysteine (SeCys) residue in the conserved sequence (-Gly-Cys-SeCys-Gly). TrxR is homodimeric protein in which each monomer includes an FAD prosthetic group, a NADPH binding site and a redox catalytic site. Electrons are transferred from NADPH via FAD and the active-site disulfide to C-terminal SeCys-containing re |
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| Immunogen | n/a |
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| Other Names | trxR1 |
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| Gene, Accession # | Entrez: 7296; Uniprot: Q16881 |
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| Catalog # | LF-MA0020 |
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| Price | |
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| Order / More Info | TrxR1 Antibody from INVITROGEN ANTIBODIES |
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| Product Specific References | PubMed: 8195224 |
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