| 产品详情 |
| Edit |   |
|---|
| Product Name | MLN-4924 |
|---|
| Description | Purity >98% by HPLC. A potent and selective inhibitor of NEDD8 (Neural precursor cell expressed, developmentally down-regulated 8)-activating enzyme (NAE) (IC50 = 4.7 nM) with potential anticancer activity. NAE activates NEDD8, an ubiquitin-like (UBL) protein that modifies cellular targets in a pathway that is parallel to but distinct from the ubiquitin-proteasome pathway (UPP). Supresses the growth of tumor xenografts in mice. |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | ((1S,2S,4R)-4-(4-(((S)-2,3-dihydro-1H-inden-1-yl)amino)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-2-hydroxycyclopentylmethyl sulfamate |
|---|
| Gene, Accession, CAS # | CAS: 905579-51-3 |
|---|
| Catalog # | LS-H3133 |
|---|
| Price | |
|---|
| Order / More Info | MLN-4924 from LIFESPAN BIOSCIENCES INC. |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|