| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Caspase 8 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | Protein A purified |
|---|
| Size | 100ul |
|---|
| Concentration | 1ug/ul |
|---|
| Applications | WB, IHC-P, IF(IHC-P), IF(ICC) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Caspase 8 Polyclonal Antibody. • Target Background: Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and C |
|---|
| Immunogen | KLH conjugated synthetic peptide derived from mouse Caspase-8 subunit p10. Immunogen Range: 430-482/482 |
|---|
| Other Names | MACH; Mch5; FLICE; CASP-8; Caspase-8; Casp8 |
|---|
| Gene, Accession # | Gene ID: 12370, SwissProt: O89110 |
|---|
| Catalog # | bs-0052R |
|---|
| Price | |
|---|
| Order / More Info | Caspase 8 Antibody from BIOSS ANTIBODIES |
|---|
| Product Specific References | Wang, G. et al. (2013). Apoptosis. 18(1):28-42. PubMed: 23054084 // Wu, C. et al. (2012) Mol Cell Biochem.359(1-2):347-58. PubMed: 21847580 // Fang, C. et al. (2014) PLoS One 9.12: e115204. PubMed: 25506932 // Tulsulkar, Jatin, et al. (2015) Transl Stroke Res. PubMed: 26573919 // Gao, Hui, et al. (2016) Am J Transl Res 8.2: 1115-1132. PubMed: 27158398 // Akinrinde, A.S., et al. (2016) J Trace Elem Med Biol. PubMed: 27259349 // Daverey, Amita, et al. (2016) Neuroscience.333:92-103. PubMed: 27423629 // Wang, Yandi, et al. (2016) Toxicol Appl Pharmacol. PubMed: 27815134 // Zhao, Yong, et al.(2016) Sci Rep. PubMed: 27883089 // Zhang, Weidong, et al. (2017) Chemosphere. PubMed: 29202267 // Pang and Fan (2016) Int.J.Ophthalmo. 9:497-504. PubMed: 27162719 // Yuan et al. (2016) Int.J.Ophthalmo. 9:505-11. PubMed: 27162720 // Peng et al. (2015) Iran.J.Pharm.Re. 14:251-61. PubMed: 25561931 |
|---|
| 产品资料 |
|
|