| 产品详情 |
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| Product Name | Dibenzylfluorescein |
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| Description | Purity >98%. Dibenzylfluorescein is a fluorogenic probe that acts as a substrate for specific cytochrome P450 (CYP) isoforms, including CYP3A4, CYP2C8, CYP2C9, CYP2C19, and aromatase (CYP19). Dibenzylfluorescein is dealkylated by these CYP isoforms to produce fluorescein benzyl ether, which is further hydrolyzed to fluorescein by the addition of base (typically 2 M NaOH). Dibenzylfluorescein is typically used near its apparent Km value of 0.87-1.9 µM. The fluorescence of fluorescein is evaluated using excitation/emission wavelengths of 485/538 nm. Dibenzylfluorescein is used to detect changes in CYP catalytic activity caused by drugs or disease. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[3-oxo-6-(phenylmethoxy)-3H-xanthen-9-yl]-benzoic acid, phenylmethyl ester, DBF, NSC 645658 |
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| Gene, Accession, CAS # | CAS: 97744-44-0 |
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| Catalog # | LS-H7434 |
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| Price | |
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| Order / More Info | Dibenzylfluorescein from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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