| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 34.2kDa. Extracellular Domain: 56-219aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). E3 ubiquitin-protein ligase that acts as a negative regulator of the Wnt signaling pathway by mediating the ubiquitination and subsequent degradation of Wnt receptor complex components Frizzled and LRP6. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the size of the intestinal stem cell zone. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | RING finger protein 203; Zinc/RING finger protein 3 |
|---|
| Gene, Accession, CAS # | ZNRF3, UniProt: Q9ULT6 |
|---|
| Catalog # | RPC23738 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Human E3 ubiquitin-protein ligase ZNRF3 (ZNRF3), partial from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|