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Product Name | Recombinant Human CSF1R / MCSF Receptor / CD115 Protein (His & GST tag) |
Description | MW: 33,248 Da. Purity >82 % as determined by SDS-PAGE. Background: M-CSFR encoded by the proto-oncogene c-fms is the receptor for colony stimulating factor 1 (CSF1R), a cytokine involved in the proliferation, differentiation, and activation of macrophages. This cell surface glycoprotein is consisted by an extracellular ligand-binding domain, a single membrane-spanning segment, and an intracellular tyrosine kinase domain. Binding of CSF1 activates the receptor kinase, leading to autophosphorylat |
Size | 0.02 mg, 0.05 mg |
Concentration | n/a |
Applications | The recombinant human CSF1R (aa 543-972) /GST chimera consists of 667 amino acids and has a calculated molecular mass of 76 KDa. It migrates as an approximately 75 KDa band in SDS-PAGE under reducing conditions. |
Other Names | [M-CSF R, CSF1R, FMS, CSFR, FIM2, C-FMS, CD115] |
Gene, Accession, CAS # | CSF1R, Gene ID: 1436, Accession: NP_005202.2 |
Catalog # | MBS2545122 |
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Order / More Info | Recombinant Human CSF1R / MCSF Receptor / CD115 Protein (His & GST tag) from MYBIOSOURCE INC. |
Product Specific References | n/a |
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