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| Product Name | Recombinant Human Bcl-2-like protein 11 |
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| Description | 1-198aa; Full Length. MW: 38.17kD. Purity >90% as determined by SDS-PAGE. Induces apoptosis and anoikis. Isoform BimL is more potent than isoform BimEL. Isoform Bim-alpha1, isoform Bim-alpha2 and isoform Bim-alpha3 induce apoptosis, although less potent than isoform BimEL, isoform BimL and isoform BimS. Isoform Bim-gamma induces apoptosis. Isoform Bim-alpha3 induces apoptosis possibly through a caspase-mediated pathway. Isoform BimAC and isoform BimABC lack the ability to induce apoptosis. |
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| Size | 0.01 mg (E-Coli), 0.01 mg (Yeast), 0.05 mg (E-Coli), 0.05 mg (Yeast), 0.1 mg (E-Coli) |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Bcl2-interacting mediator of cell death] |
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| Gene, Accession, CAS # | BCL2L11, Gene ID: 10018, Accession: NP_001191035.1 |
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| Catalog # | MBS1094348 |
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| Order / More Info | Recombinant Human Bcl-2-like protein 11 from MYBIOSOURCE INC. |
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| Product Specific References | Bima novel member of the Bcl-2 family that promotes apoptosis.O'Connor L., Strasser A., O'Reilly L.A., Hausmann G., Adams J.M., Cory S., Huang D.C.S.EMBO J. 17:384-395(1998) Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family.Mami U., Miyashita T., Shikama Y., Tadokoro K., Yamada M.FEBS Lett. 509:135-141(2001) Identification and characterization of Bimgamma, a novel proapoptotic BH3-only splice variant of Bim.Liu J.-W., Chandra D., |
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