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Product Name | Recombinant Human Bcl-2-like protein 1 |
Description | 1-209aa; Partial. MW: 39.4kD. Purity >90% as determined by SDS-PAGE. Potent inhibitor of cell death. Inhibits activation of caspases. Appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. Also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis. Isoform Bcl-X(L) also regulates presynaptic plasticity, including neurotransmitter |
Size | 0.01 mg (E-Coli), 0.05 mg (E-Coli), 0.1 mg (E-Coli), 0.2 mg (E-Coli), 0.5 mg (E-Coli) |
Concentration | n/a |
Applications | n/a |
Other Names | [Apoptosis regulator Bcl-X] |
Gene, Accession, CAS # | BCL2L1, Gene ID: 598, Accession: NP_001182.1 |
Catalog # | MBS969476 |
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Order / More Info | Recombinant Human Bcl-2-like protein 1 from MYBIOSOURCE INC. |
Product Specific References | bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death.Boise L.H., Gonzalez-Garcia M., Postema C.E., Ding L., Lindsten T., Turka L.A., Mao X., Nunez G., Thompson C.B.Cell 74:597-608(1993) |
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