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| Product Name | Recombinant Human Toll/interleukin-1 receptor domain-containing adapter protein (TIRAP) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 50.9kDa. Full Length: 1-221aa. N-terminal GST-tagged. Homo sapiens (Human). Adapter involved in TLR2 and TLR4 signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha and interleukin-6. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Adaptor protein Wyatt; MyD88 adapter-like protein |
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| Gene, Accession, CAS # | TIRAP, UniProt: P58753 |
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| Catalog # | RPC22125 |
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| Order / More Info | Recombinant Human Toll/interleukin-1 receptor domain-containing adapter protein (TIRAP) from BIOMATIK |
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| Product Specific References | n/a |
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