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| Product Name | Recombinant Human Trichoplein keratin filament-binding protein (TCHP) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 77.1kDa. Full Length: 1-498aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. Inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Mitochondrial protein with oncostatic activity; Mitostatin; Tumor suppressor protein |
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| Gene, Accession, CAS # | TCHP, UniProt: Q9BT92 |
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| Catalog # | RPC23628 |
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| Order / More Info | Recombinant Human Trichoplein keratin filament-binding protein (TCHP) from BIOMATIK |
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| Product Specific References | n/a |
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