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| Product Name | PIP5K1A, Active |
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| Description | Full length. MW: 86 kDa. Description: Recombinant full-length human PIP5K1A was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.Scientific Background: PIP5K1A or phosphatidylinositol-4-phosphate 5-kinase 1 alpha phosphorylates phosphatidylinositol-4-phosphate to form phosphatidylinositol 4,5-bisphosphate. PIP5K1 is required for Wnt3a-induced LRP6 phosphorylation at ser1490 in mammalian cells (1). Wnt3a stimulates the formation of phosphatidylinositol 4,5-bisphosphate |
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| Size | 0.005 mg, 0.01 mg |
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| Concentration | n/a |
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| Applications | Kinase Assay |
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| Other Names | [Homo sapiens phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, mRNA; Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; phosphatidylinositol 4-phosphate 5-kinase type-1 alpha; phosphatidylinositol-4-phosphate 5-kinase type 1 alpha; 68 kDa type I phosphatidylinositol 4-phosphate 5-kinase alpha; Phosphatidylinositol 4-phosphate 5-kinase type I alpha; PIP5KIalpha] |
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| Gene, Accession, CAS # | PIP5K1A , Gene ID: 8394, Accession: BC007833 |
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| Catalog # | MBS515570 |
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| Order / More Info | PIP5K1A, Active from MYBIOSOURCE INC. |
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| Product Specific References | 1. Pan, W. et al: Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation. Science 321: 1350-1353, 2008. 2. Barrero-Villar M, PI4P5-kinase Ialpha is required for efficient HIV-1 entry and infection of T cells. J Immunol. 2008 Nov 15;181 (10):6882-8. |
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