| 产品详情 |
| Edit |   |
|---|
| Product Name | Recombinant Mannheimia haemolytica Leukotoxin (lktA), partial |
|---|
| Description | Purity > 90% as determined by SDS-PAGE. MW: 28kDa. Partial: 715-953aa. N-terminal 6xHis-tagged. Mannheimia haemolytica (Pasteurella haemolytica). Pasteurella leukotoxins are exotoxins that attack host leukocytes and especially polymorphonuclear cells, by causing cell rupture. The leukotoxin binds to the host LFA-1 integrin and induces a signaling cascade leading to many biological effects, including tyrosine phosphorylation of the CD18 tail, elevation of the intracellular Ca2+ and lysis of the host cell. This leukotoxin is a major contributor to the pathogenesis of lung injury in ovine pneumonic pasteurellosis. It has also weak holytic activity. |
|---|
| Size | 100ug |
|---|
| Concentration | n/a |
|---|
| Applications | RUO |
|---|
| Other Names | n/a |
|---|
| Gene, Accession, CAS # | lktA, UniProt: P0C085 |
|---|
| Catalog # | RPC25078 |
|---|
| Price | |
|---|
| Order / More Info | Recombinant Mannheimia haemolytica Leukotoxin (lktA), partial from BIOMATIK |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|