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| Product Name | Recombinant Human Dickkopf-related protein 2 (DKK2) |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 41kDa. Full Length of Mature Protein: 34-259aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmbrane protein KREN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | n/a |
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| Gene, Accession, CAS # | DKK2, UniProt: Q9UBU2 |
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| Catalog # | RPC23576 |
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| Order / More Info | Recombinant Human Dickkopf-related protein 2 (DKK2) from BIOMATIK |
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| Product Specific References | n/a |
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