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| Product Name | Polymyxin B1 Isoleucine |
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| Description | Purity >90%. The polymyxins are cationic peptides originally isolated from B. polymyxa . They bind and kill Gram-negative bacteria. The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B1 Isoleucine differs from polymyxin B1 by having isoleucine rather than leucine as a component of the cyclic peptide. Polymyxin B1 isoleucine is comparable to other B polymyxins in its ability to kill P. aeruginosa, A. baumannii, and K. pneumoniae isolates. Its relative pharmacokinetics and nephrotoxicity have not been examined. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-((S)-4-amino-1-(((2S,3R)-1-(((S)-4-amino-1-oxo-1-(((3S,6S,9S,12S,15R,18S,21S)-6,9,18-tris (2-aminoethyl)-15-benzyl-12-((S)-sec -butyl)-3-((R)-1-hydroxyethyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl)amino)butan-2-yl)amino |
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| Gene, Accession, CAS # | CAS: 80469-10-9 |
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| Catalog # | LS-H9471 |
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| Order / More Info | Polymyxin B1 Isoleucine from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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