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| Product Name | Recombinant Mouse NACHT, LRR and PYD domains-containing protein 3 (Nlrp3), partial |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 34.2kDa. Partial: 1-153aa. N-terminal 6xHis-SUMO-tagged. Mus musculus (Mouse). May function as an inducer of apoptosis. Interacts selectively with ASC and this complex may function as an upstream activator of NF-kappa-B signaling. Inhibits TNF-alpha induced activation and nuclear translocation of RELA/NF-KB p65. Also inhibits transcriptional activity of RELA (By similarity). Activates caspase-1 as part of the NALP3 inflammasome complex in response to a number of triggers including bacterial or viral infection which leads to processing and release of IL1B and IL18. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Cold autoinflammatory syndrome 1 protein homolog; Cryopyrin; Mast cell maturation-associated-inducible protein 1; PYRIN-containing APAF1-like protein 1 |
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| Gene, Accession, CAS # | Nlrp3, UniProt: Q8R4B8 |
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| Catalog # | RPC23337 |
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| Price | |
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| Order / More Info | Recombinant Mouse NACHT, LRR and PYD domains-containing protein 3 (Nlrp3), partial from BIOMATIK |
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| Product Specific References | n/a |
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