| 产品详情 |
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| Antigenic Specificity | alpha-Methylacyl-CoA Racemase (AMACR) |
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| Clone | 2A10F3 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG2b |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Western Blotting (WB),Immunohistochemistry (IHC),Immunocytochemistry (ICC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AMACR (alpha-methylacyl-CoA racemase) has been recently described as prostate cancer-specific gene that encodes a protein involved in the beta-oxidation of branched chain fatty acids. Expression of AMACR protein is found in prostatic adenocarcinoma but not in benign prostatic tissue. It stains premalignant lesions of prostate: high-grade prostatic intraepithelial neoplasia (PIN) and atypical adenomatous hyperplasia. AMACR can be used as a positive marker for PIN. Defects in AMACR are the cause of congenital bile acid synthesis defect type 4 (CBAS4), also known as cholestasis, intrahepatic, with defective conversion of trihydroxycoprostanic acid to cholic acid or trihydroxycoprostanic acid in bile. Clinical features include neonatal jaundice, intrahepatic cholestasis, bile duct deficiency and absence of cholic acid from bile. |
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| Immunogen | Purified recombinant fragment of human AMACR expressed in E. coli. |
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| Other Names | AMACR|DKFZp469O1232|amacr|NCU04099.1|MGC89832|AMACRD|CBAS4|RACE|RM|Macr1|Da1-8|Marc1 |
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| Gene, Accession # | Gene ID: 23600,17117 |
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| Catalog # | ABIN968957 |
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| Price | |
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| Order / More Info | alpha-Methylacyl-CoA Racemase (AMACR) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 16500022, 16469560 |
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