| 产品详情 |
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| Product Name | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit beta |
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| Description | Purity > 90% as determined by SDS-PAGE. MW: 16.4kDa. Full Length of Mature Protein: 24-146aa. N-terminal 6xHis-tagged. Calloselasma rhodostoma (Malayan pit viper) (Agkistrodon rhodostoma). Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the Cytoplasmic domain tail of CLEC1B, which promotes the binding of spleen tyrosine kinase (Syk), subsequent activation of PLCgamma2, and platelet activation and aggregation. Binding to GPIbalpha (GP1BA) and alpha2/beta-1 (ITGA2/ITGB1) may also induce aggregation, but this is controversial. |
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| Size | 100ug |
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| Concentration | n/a |
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| Applications | RUO |
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| Other Names | Aggretin beta chain; Rhodoaggretin subunit beta |
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| Gene, Accession, CAS # | UniProt: Q9I840 |
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| Catalog # | RPC25530 |
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| Price | |
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| Order / More Info | Recombinant Calloselasma rhodostoma Snaclec rhodocytin subunit beta from BIOMATIK |
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| Product Specific References | n/a |
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