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| Antigenic Specificity | Neurofilament, Light Polypeptide (NEFL) |
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| Clone | NF-68 |
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| Host Species | Mouse |
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| Reactive Species | human, porcine, rat |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Immunohistochemistry (Frozen Sections) (IHC (fro)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 kD(NFL), 125 kD(NFM) and 200 kD(NFH) on SDS-gel electrophoresis. And they have a role in the maturation of regenerating myelinated axons. Neurofilament 68(NF68), also called Neurofilament Protein, Light Chain(NFL). It is one of the most abundant cytoskeletal components of the neuron. Mutations in this gene were reported as a cause for autosomal dominant Charcot-Marie-Tooth type 2E(CMT2E) linked to chromosome 8p21. NFL was identified repeatedly in both screenings and found to interact with Myotubularin-related 2 gene, MTMR2 in both Schwann cells and neurons. |
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| Immunogen | Pig spinal cord. |
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| Other Names | NEFL|nefl|zgc:136626|AI847934|CMT2E|NF-L|NF68|Nfl|CMT1F|NFL|XNF-L |
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| Gene, Accession # | Gene ID: 4747,100521224,83613 |
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| Catalog # | ABIN343549 |
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| Price | |
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| Order / More Info | Neurofilament, Light Polypeptide (NEFL) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 12566280, 9398473 |
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