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| Product Name | Recombinant Human Tax1-binding protein 3 |
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| Description | 1-124aa; Full Length. MW: 41.1kD. Purity >90% as determined by SDS-PAGE. May regulate a number of protein-protein interactions by competing for PDZ domain binding sites. Binds CTNNB1 and may thereby act as an inhibitor of the Wnt signaling pathway. Competes with LIN7A for KCNJ4 binding, and thereby promotes KCNJ4 internalization. May play a role in the Rho signaling pathway. May play a role in activation of CDC42 by the viral protein HPV16 E6. |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [Glutaminase-interacting protein 3; Tax interaction protein 1; TIP-1; Tax-interacting protein 1] |
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| Gene, Accession, CAS # | TAX1BP3, Gene ID: 30851, Accession: NP_001191627.1 |
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| Catalog # | MBS717133 |
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| Order / More Info | Recombinant Human Tax1-binding protein 3 from MYBIOSOURCE INC. |
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| Product Specific References | The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins.Rousset R., Fabre S., Desbois C., Bantignies F., Jalinot P.Oncogene 16:643-654(1998) The genomic region encompassing the nephropathic cystinosis gene (CTNS)complete sequencing of a 200-kb segment and discovery of a novel gene within the common cystinosis-causing deletion.Touchman J.W., Anikster Y., Dietrich N.L., Maduro V.V.B., McDowell G., Shotelersuk V., Bouffard G.G., Beckstrom-Sternberg |
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