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Product Name | Recombinant Human Noggin / NOG Protein (His tag) |
Description | MW: 25,774 Da. Purity >95 % as determined by SDS-PAGE. Background: Noggin is a secreted protein involved at multiple stages of vertebrate embryonic development including neural induction and is known to exert its effects by inhibiting the bone morphogenetic protein (BMP)-signaling pathway. It binds several BMPs with very high (picomolar) affinities, with a marked preference for BMP2 and BMP4 over BMP7. By binding tightly to BMPs, Noggin prevents BMPs from binding their receptors. Noggin binds th |
Size | 0.02 mg, 0.1 mg |
Concentration | n/a |
Applications | The recombinant human Noggin comprises 216 amino acids after removal of the signal peptide and has a predicted molecular mass of 24.6 kDa. As a result of glycosylation, rhNoggin migrates as an approximately 30 kDa bnd in SDS-PAGE under reducing conditions. |
Other Names | [NOG, SYM1, SYNS1] |
Gene, Accession, CAS # | NOG, Gene ID: 9241, Accession: NP_005441.1 |
Catalog # | MBS2546372 |
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Order / More Info | Recombinant Human Noggin / NOG Protein (His tag) from MYBIOSOURCE INC. |
Product Specific References | n/a |
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