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Product Name | Linsitinib, Free Base |
Description | Linsitinib, Free Base. Linsitinib is also known as OSI-906, is a novel, potent small-molecule dual insulin-like growth factor-1 receptor (IGF-1R)/insulin receptor (IR) kinase inhibitor. Linsitinib inhibited IGF-1R and IR kinases with IC50 values of 35 nM and 75 nM, respectively. Linsitinib showed superior efficacy compared with MAB391, a selective anti-IGF-1R antibody, in human tumor xenograft models in which both IGF-1R and IR were phosphorylated. MW: 421.49 g/mol. Purity >99% pure |
Size | 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 300 mg |
Concentration | n/a |
Applications | n/a |
Other Names | OSI-906, OSI-906AA, OSI906, ASP-7487 |
Gene, Accession, CAS # | CAS: 867160-71-2 |
Catalog # | orb153620 |
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Order / More Info | Linsitinib, Free Base from BIORBYT LTD. |
Product Specific References | n/a |
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